The Helicobacter Pylori Research Group aims to advance the understanding of the prevention, diagnosis and treatment of H. pylori.

Helicobacter pylori is the most common human pathogen, infecting half of the world's population. It is the proven cause of peptic ulcer.

The health problem is magnified in Asia where virulent strains are common, leading to frightening rates of gastric cancer. Antibiotic-resistant strains of H. pylori are no longer responding to routine drug treatments.

The Helicobacter Pylori Research Group is taking up the challenge to develop new diagnostics and treatments to target H. pylori across the globe. The research team is focused on the prevention, diagnosis and treatments of H. pylori using clinical microbiology, molecular biology, immunology, genomics and systems biology. Our current research projects include:

  • How can we best treat antibiotic strains of H. pylori?
  • How many strains of H. pylori are resistant to antibiotics?
  • Where are the H. pylori 'hot spots' in WA and the world?
  • Why are antibiotic resistant strains of H. pylori more common in some population groups than others?
  • Why are Indigenous Australians, the elderly and migrants more likely to be infected with H. pylori?
  • Which genetic changes lead to antibiotic resistance in H. pylori?
  • How can we apply next generation sequencing technology to discover better diagnostic tests?
  • How has H. pylori evolved and moved around the globe?
  • How does H. pylori's cancer causing gene CagA interact with other cells?

Super-diagnostics for other superbugs

The WHO has warned that "antibiotic resistance is an increasingly serious threat to global public health". It affects our ability to combat many serious infections, not just H. pylori. Not only that the organisation had listed H. pylori as a Group I human carcinogen, H. pylori is also recently listed as one of top 12 antibiotic resistant bacteria posing the greatest threat to human health. The new technology and approaches used to develop better diagnostics for H. pylori can also be applied to the fight against other superbugs.

The Helicobacter Foundation

The "Helicobacter Foundation" was founded by Prof. Barry J. Marshall in early 1994, and is dedicated to providing you with the latest information about Helicobacter pylori, its diagnosis, treatment and clinical perspectives. The story of why it took 100 years to discover Helicobacter is described in these pages.

A forum was created to allow everyone in the world to connect with Prof. Barry J. Marshall. If you have a question about H. pylori, feel free to visit the forum and ask a question there.

Link to Helicobacter Foundation website: www.helico.com 

Link to Helicobacter Foundation forum: www.helico.com/forums 

Link to FAQ about H. pylori infection and treatment: www.helico.com/welcome.html 

Further information

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