Interstitial cystitis (often called painful bladder syndrome) is a chronic, painful and perplexing bladder problem. It is characterised by painful, frequent and urgent urination. In severe cases, sufferers urinate as many as 60 times per day. IC-BPS has a significant impact on quality of life, with the condition most frequently presenting in women. 

IC-PBS is a poorly understood condition and is tricky to diagnose. Interstitial cystitis has a long-lasting impact on quality of life and there is currently no cure, although medications and other therapies may offer some relief. Over 64,000 Australians are diagnosed with IC-PBS, a figure grossly under-representative of the scale of the problem, due to the stigma and embarrassment of reporting bladder conditions.

The primary purpose of this research was to improve our understanding of IC-BPS through studying urinary bladder wall measurements in 120 healthy volunteers using modern High Frequency Ultrasound. The project used new ultrasound technology to provide a comprehensive examination of the bladder, including new and novel insights into bladder wall thickness and layers, tissues elastography and resistive index measures. This is the first time that this technology has been used to study the bladder and the near atomic level images provide a whole new window into studying IC-PBS. 

Thank you to the volunteers that participated in our study. We are grateful for your contribution. We hope that our study has contributed to the search for a longterm cure for IC-PBS.

This project has now concluded. More information is available on the website